Services
3-D cell/tissue organoid-models are engineered from primary human, veterinary or insect cell lines. We strive to develop the models with cell lines obtained from commercial sources or developed from in-house proprietary cell lines.
In those cases, where cell lines are not commercially available, we will contact commercial sources to acquire tissues with IRB/IACUC approved protocols. Relevant cells are isolated from the targeted in vivo tissue. These cells are propagated, characterized and utilized in the model development.
Our 3-D cell/tissue model service package:
Cell Systems 3-D scientists, collaborate with the investigator to design an unique prototype 3-D in vitro cell/tissue organoid- like model specific to their requirements. Cell lines are acquired, propagated and the 3-D model is engineered using Good Tissue Practices (GTP).
Cell Systems 3-D service package provides to the investigator:
- Consultation throughout the design process
- Acquisition of relevant cells
- Engineering of the 3-D model within our laboratory
- 3 prototype models and 3 investigative models
- Phenotype and functionality characterization of all cells and 3-D model
- Shipment of the 3-D model to the investigator
We provide the investigator the prototype 3-D cell/tissue organoid-like model within 60 to 90 days for initial evaluation. We deliver up to 2 additional prototype 3-D models, as needed, for the investigator’s final approval. Upon approval, 3 investigative 3-D models are delivered on a monthly basis.
The cost for design, bioengineering, phenotypic and functionality characterization, 3 prototype and 3 investigative models is between $(USD) 75,000 to 100,000 dependent on tissue complexity . Additional same-tissue investigative 3-D models are provided for a nominal charge.